sign and symptom of diabetes Progression of insulin resistance can lead to metabolic syndrome, nonalcoholic fatty liver disease (NAFLD), and type 2 diabetes mellitus.blood sugar correction
The researchers looked at data from 9,000 adults, ages 20 years and older, from the 2005-2014 National Health and Nutrition Examination Survey (NHANES). The information collected by the research team included body weight (based on body mass index [BMI]) and blood test results.
Based on the fasting blood glucose test and the OGTT, 765 patients were diagnosed as having type 2 diabetes (T2D). However, only about 27% of these individuals were classified as having diabetes based on their A1c levels, which is how Dr. Villacreses and her team determined that nearly three-quarters of those at risk for diabetes were not aware that they had this chronic disease, and therefore were not receiving treatment.1
sign and symptom of diabetes overview (🔴 is characterized by) | sign and symptom of diabetes take insulinhow to sign and symptom of diabetes for "" she tells EndocrineWeb. While the A1c test is convenient, ''we recommend that we do not rely solely on this number,""We wanted to bring this up to emphasize the gap [in the accuracy of detection],""
"" she says. So an A1c can be done so long as you are then advised to have another test to check your blood sugar levels if there is any concern regarding your risks.
To fully understand the reason that problems arise with the reliability of the A1c test, Dr. Christofides explains that when circulating glucose builds up in the blood, it binds to the hemoglobin molecule in the red blood cell, and the A1c measures how much glucose is bound.
As the differences found among different patient populations, she says that genetic mutations are more likely to occur in certain ethnicities, which alter the way the glucose binds to the hemoglobin molecule—thereby giving false readings more often. African Americans, for instance, carry a variant form of a gene for the sickle cell anemia that is involved in abnormal binding of blood glucose, she says, so the A1c test is artificially lower than expected in these patients.
For individuals who haven’t received a diagnosis of diabetes, Dr. Villacreses says, one important lesson from these fidings is that ''you should not feel 100% reassured if your A1c number is less than 6.5% that you are do not have diabetes.” A test result that is greater than 6.4% defines the beginning of diabetes, so you may have prediabetes or have already progressed to the 1 last update 30 May 2020 type 2 diabetes.For individuals who haven’t received a diagnosis of diabetes, Dr. Villacreses says, one important lesson from these fidings is that ''you should not feel 100% reassured if your A1c number is less than 6.5% that you are do not have diabetes.” A test result that is greater than 6.4% defines the beginning of diabetes, so you may have prediabetes or have already progressed to type 2 diabetes.
The sooner you receive a diagnosis regarding your diabetes status, the earlier treatment can begin. This is important because by understanding your risks, and making the necessary lifestyle changes, you can prevent prediabetes from progressing or even reverse the type 2 diabetes.
In addition, she says, patients should feel comfortable asking their doctor about the choice of tests and indicate your desire to skip the A1c, and have one of the other more reliable screening methods, while more time consuming, to determine if you are at risk for pre-diabetes or diabetes.
Dr. Villacreses has received research funding and speaking fees from a variety of pharmaceutical companies but none that pose a conflict in this research. Dr. Christofides has no relevant financial disclosures.